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PDE5 inhibitorBrand: LevitraGeneric available

Vardenafil (Levitra) review

A close cousin of sildenafil, now mostly a second choice

7.2out of 10

Our overall score

Written by The ED Watch Editorial Board

Medical review pending · Source-based editorial draft

Sources checked

The short version

Vardenafil behaves much like sildenafil — similar onset, a slightly longer window, similar side effects. Brand-name Levitra has largely disappeared from US pharmacy shelves, but generic vardenafil remains available and is a reasonable option if sildenafil has not worked well for you.

Best for: People for whom sildenafil was ineffective or poorly tolerated, and who don't want tadalafil's long duration.

What works

  • A genuine alternative if sildenafil under-delivers
  • Slightly longer effective window than sildenafil
  • Available as an orally disintegrating tablet for people who dislike swallowing pills

What to watch

  • Brand-name Levitra has largely been withdrawn from the US market
  • Generic costs more than sildenafil for no clear advantage in most cases
  • Carries a QT-prolongation caution the others largely do not
  • Fatty meals interfere with absorption

Get emergency help for these

  • An erection lasting more than 4 hours — this can cause permanent damage
  • Sudden loss of vision or hearing
  • Chest pain during or after sex — tell responders you took a PDE5 inhibitor

At a glance

Generic name
Vardenafil
Brand name
Levitra
Drug class
PDE5 inhibitor
FDA approved
2003
Typical doses
5 mg, 10 mg, 20 mg (plus a 10 mg orally disintegrating tablet)
Usual starting dose
10 mg as needed
Onset
30–60 minutes
Duration
4–8 hours
Half-life
~4–5 hours
Effect of food
A high-fat meal reduces and delays absorption
Generic available
Yes
Typical cost
Roughly $1–$8 per tablet for the generic with a discount cardChecked July 15, 2026. Prices vary widely by pharmacy — treat as a ballpark, not a quote.

Levitra, generic vardenafil, and Staxyn are not three unrelated medicines

Vardenafil is the generic drug name associated with Levitra. Staxyn refers to an orally disintegrating vardenafil formulation. When comparing reviews, establish whether the writer used a film-coated tablet, a dissolving tablet, or a compounded product. Similar names do not establish interchangeable instructions.

Vardenafil 5 mg, 10 mg, and 20 mg reviews

The film-coated tablet label lists 10 mg as the usual starting dose, with adjustment to 5 mg or 20 mg according to response and tolerability. Lower limits apply in some circumstances. A favorable 20 mg testimonial is not a reason to increase a 5 mg prescription.

Listings for Levitra 30 mg, 40 mg, 80 mg, or 100 mg should not be read as standard labeled ED dosing. Ask a pharmacist to verify the medication and formulation. Do not confuse sildenafil's strengths with vardenafil's, even when a seller groups the products together.

Does generic Levitra work, and is it safe?

The useful questions are whether the dispensed medicine is an approved product, whether it is appropriate for you, and whether you are following its specific instructions. The label includes a particular caution for congenital long-QT syndrome and certain antiarrhythmic medicines, alongside contraindications such as nitrates. A generic product does not remove those cautions.

For a price comparison, request the same formulation, strength, and tablet count from each pharmacy. For an inadequate response, bring timing, meals, effects, and your medication list to the prescriber. Personal reviews can describe an experience; they cannot establish that a particular manufacturer's tablets will work better for you.

Where vardenafil fits

Vardenafil arrived in 2003, the same year as tadalafil, and is chemically very close to sildenafil. In practice the two behave similarly: comparable onset, a similar side effect profile, and a window that is perhaps modestly longer.

It has become a second-line choice mostly for commercial reasons rather than clinical ones. Brand-name Levitra has been largely withdrawn from the US market, and generic vardenafil is stocked less widely and priced above generic sildenafil. If sildenafil works for you, there is usually no reason to switch. If it doesn't, vardenafil is a sensible next thing to try — individual response to PDE5 inhibitors varies more than the population averages suggest.

The orally disintegrating tablet

Vardenafil is also sold as a 10 mg orally disintegrating tablet (marketed as Staxyn) that dissolves on the tongue without water.

Dosing

Usual start
10 mg about an hour before sex
Range
5 mg to 20 mg, adjusted for response and tolerance
Frequency
No more than once in 24 hours
Food
Avoid heavy, fatty meals near the dose
Age 65+
A 5 mg starting dose is often recommended

Safety and interactions

Vardenafil carries one caution that sets it apart from the rest of the class: it can prolong the QT interval on an ECG. That matters if you have a known QT abnormality or take medications that lengthen it.

  • Class IA antiarrhythmics (quinidine, procainamide) or class III (amiodarone, sotalol) — avoid the combination
  • Congenital long QT syndrome — vardenafil is generally not recommended
  • Riociguat (Adempas) — contraindicated
  • Strong CYP3A4 inhibitors — significant dose reductions apply, and some combinations are not recommended at all
  • Alpha blockers — stable dosing first, then start vardenafil low

Side effects

Headache, flushing, nasal congestion, and indigestion are the common ones, at rates broadly similar to sildenafil. Visual disturbances occur but are less frequent than with sildenafil. As with the whole class, an erection lasting more than four hours, or sudden vision or hearing loss, requires emergency care.

Common questions

What is Levitra's generic name?

Vardenafil. Check the formulation as well as the name: film-coated and orally disintegrating tablets have different labeling.

Is Staxyn interchangeable with Levitra 10 mg?

No. The orally disintegrating vardenafil label says exposure differs from the 10 mg film-coated tablet and the products are not interchangeable.

Is Levitra 100 mg a standard dose?

No. The film-coated vardenafil label describes adjustment up to 20 mg, with lower limits for some patients. Have a pharmacist check any listing or package claiming a much higher strength.

Do generic Levitra reviews prove one manufacturer is better?

Anecdotes do not establish a reliable comparison. Match formulation and strength and discuss a suspected medication problem with the dispensing pharmacist.

Is Levitra still available?

Brand-name Levitra has largely been withdrawn from the US market, but generic vardenafil is still available by prescription. Stocking varies by pharmacy, so it may need to be ordered.

Is vardenafil stronger than sildenafil?

It is more potent on a milligram basis — 10 mg of vardenafil is roughly comparable to 50 mg of sildenafil — but that is a difference in dosing units, not in how well it works. Comparative trials show broadly similar effectiveness.

Why would I take vardenafil instead of sildenafil?

Mainly if sildenafil didn't work well or caused side effects you couldn't tolerate. Response to individual PDE5 inhibitors varies between people, so a drug in the same class can still perform differently for you.

Can I take vardenafil with food?

You can, but a high-fat meal reduces how much drug is absorbed and delays onset. A light meal is much less of a problem than a heavy one.

Sources

  1. 1.Vardenafil film-coated tablets: prescribing informationDailyMed / National Library of Medicine
  2. 2.Vardenafil orally disintegrating tablets: prescribing informationDailyMed / National Library of Medicine
  3. 3.Levitra (vardenafil hydrochloride) prescribing informationU.S. Food and Drug Administration
  4. 4.Erectile Dysfunction: AUA GuidelineAmerican Urological Association