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Treatment reviews

Treatments that aren't a pill

Compare gels, devices, procedures, and therapy by the evidence, practical demands, and questions to discuss with a clinician. Treatment choice depends on your circumstances and preferences.

7.7out of 10

Trimix and Bimix injections

Injection therapyWorks when pills don'tCompounded — not FDA-approved

The most effective ED treatment there is, and the one nobody advertises

Cost
Often $50–$150 per vial, which typically yields many doses — commonly a few dollars per use
7.6out of 10

Penile implants

SurgeryHighest satisfaction ratesIrreversible

The end of the road, and the treatment people are gladdest they had

Cost
Frequently covered by insurance once conservative treatment has failed; tens of thousands of dollars without coverage
7.4out of 10

Vacuum erection devices

Vacuum pumpNo drug interactionsNo prescription required

Unglamorous, drug-free, and it works when the pills don't

Cost
Roughly $100–$500 for a medical-grade device, as a one-time purchase
6.6out of 10

Constriction rings and wearable ED devices

Wearable deviceNo prescription neededSafe with nitrates

The cheapest thing that works, if your problem is holding an erection rather than getting one

Cost
Purpose-built devices run roughly $100–$200; Eddie is priced around $188 for a four-month cycle
Unscored

Eroxon (MED3000) topical gel

OTC topical gelOTC topical deviceNo prescription needed

An OTC ED gel: what MED3000 contains, how it is used, and what reviews can tell you

Cost
Retailer-dependent price per box; divide by the number of single-use tubes
5.4out of 10

Testosterone replacement therapy

Hormone therapyOnly for confirmed low testosteroneSuppresses fertility

Real medicine for a real condition — and the wrong answer for most people who ask about it

Cost
Generic injections are inexpensive; gels, pellets, and oral forms cost substantially more, plus ongoing lab monitoring
Unscored

Shockwave therapy (Li-ESWT)

Clinic procedureMixed evidenceCheck the exact device

Focused shockwaves, radial waves, and home devices need different evidence

Cost
Clinic-specific course pricing; obtain a written total including any proposed maintenance
4.0out of 10

PT-141 (bremelanotide)

PeptideNot approved for menActs on desire, not blood flow

An approved drug — for women. Sold to men by clinics that do not always mention that

Cost
Varies widely; wellness-clinic peptide programmes are typically expensive and cash-pay
2.1out of 10

Herbal and OTC “male enhancement” supplements

OTC supplementNot recommendedFrequently adulterated

The only category here where the products that work are the ones breaking the law

Cost
Commonly $30–$80 a month, frequently more than FDA-approved generic sildenafil costs
Unscored

Pelvic floor physical therapy

Physical therapyNo medication requiredLimited evidence

A supervised rehabilitation option with promising, limited ED evidence

Cost
Clinic-specific evaluation and follow-up fees; request an estimate and check insurance
Unscored

Sex therapy and counseling for ED

Psychological therapyCan accompany medical careNo medication required

Support for the anxiety, stress, and relationship side of erection difficulties

Cost
Therapist-specific session fees or insurance cost-sharing; request a written estimate

Why this section exists

These options solve different problems and come with different commitments. A device purchase, a course of therapy, and a procedure should be compared on their own evidence. New source-based reviews remain unscored, with medical review status shown on each page.